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In naturally aged mouse models (1820 months old), daily oral administration of 5-amino-1mq capsules for 12 consecutive weeks significantly reduced NNMT activity and increased NAD+ levels in various tissues (liver, kidney, adipose tissue), along with markedly elevated expression of SIRT1 and SIRT3 proteins
No evidence of hormonal, hepatic, or systemic adverse effects has been observed in available research data
The mechanism behind this healing is angiogenesisthe physiological process through which new blood vessels form from pre-existing vessels
For borderline results, additional testing with holotranscobalamin or methylmalonic acid/homocysteine levels may be appropriate
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