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Thymosin beta-4 ophthalmic solution improved signs and symptoms of severe dry eye in a randomized phase 2 trial and promoted corneal healing in a randomized, placebo-controlled, double-masked phase 3 trial in neurotrophic keratopathy
Derivation of brain capillary-like endothelial cells from human pluripotent stem cell-derived endothelial progenitor cells
Yu K et al
In addition, commercially available products may present other limitations : Fixed dosing that does not allow for gradual titration Lack of preservative-free or dye-free options Absence of certain medications in oral form in the United States Limited flexibility in combining therapies to match multisystem symptom patterns In many MCAS cases, therapies cannot be fully implemented using commercially manufactured products alone
10.1016/j.heares.2004.10.011
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