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The oral formulation tested in the Phase IIb trial used doses of 1 to 20 mg daily [3]
B12 may accelerate red blood cell production in ways that may be harmful in this condition Use during pregnancy or breastfeeding should occur only if a licensed healthcare provider determines that potential benefits outweigh potential risks
doi: 10.1210/jc.2010-1587
This recommendation is particularly apt when the compound in question lacks any pediatric approval or trial data
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