CPT II Type 1 "muscle" phenotype, which is the most frequent clinical presentation, is characterized by recurrent episodes of muscle pain, rhabdomyolysis (a potentially fatal disease that occurs suddenly and with great force destroying skeletal muscle) and myoglobinuria
Based on the 2026 Clinical Obesity review of 480,825 adults, the most commonly deficient nutrients in GLP-1 users are vitamin D (13.6% deficient by 12 months), iron (2630% lower ferritin than comparators), calcium, and B12
10.1002/mds.27115 348 ObrenovichM.JaworskiH.TadimallaT.MistryA.SykesL.PerryG.et al
Proteomics 18:e1800008 Park E, Chung SW (2019) ROS-mediated autophagy increases intracellular iron levels and ferroptosis by ferritin and transferrin receptor regulation
If the primary complaint is difficulty initiating sleep, DSIP addresses that more directly