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For states of systemic inflammation that involve cells of the peripheral immune system, while for neurodegenerative and neuroinflammatory diseases such as AD, PD, and MS, penetration of the CNS is necessary (Lin et al., 2024
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In addition, vitamin E is able to induce the expression of intercellular adhesion molecule (ICAM-1) by oxidized LDL in endothelial cells (Cominacini et al
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Therefore, high level of testicular folate upon supplementation is likely to improve its antioxidant capacity
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