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They may focus solely on weight loss, skipping a full review of your medical history including other medications, underlying conditions, or factors contributing to weight gain

However, this should not be relied upon as a primary strategy for managing steroid-induced hyperglycaemia

The most common side effects are stomach-related, including nausea, vomiting, diarrhea, constipation, and abdominal pain

The cellular protection of -cells and hepatocytes is well-supported by in vitro and animal data, anti-steatohepatitis effects are supported, while reversal of established fibrosis remains uncertain pending more definitive phase 3 outcomes ( Despite ongoing clinical characterization of these structural modifications, the evidence is clear that these intracellular cascades translate into robust systemic improvements that have redefined the standard of care ( The alignment of these systemic clinical outcomes with the preservation of intracellular structures underscores a profound integration of endocrine control and organellar maintenance

16S rRNA gene sequencing data were deposited in the National Library of Medicine National Center for Biotechnology Information (Accession numbers are PRJNA1032695 and PRJNA1087524), and are publicly available