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An initial decline in eGFR is common after treatment initiation but typically stabilizes over time, contributing to long-term preservation of kidney function [108]
Following burn or traumatic injury, the risk typically begins about 48 hours after injury, peaks at 7 to 10 days, and may persist for up to 2 years
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Additionally, non-insulinotropic effects like regulating the survival and proliferation of pancreatic beta cells can be facilitated by GIP receptor activation [64, 65]
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