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However, specific chemotherapeutic agents can induce immunogenic cell death (ICD), characterized by the release of damage-associated molecular patterns (DAMPs) that prime antitumor T cell responses (43, 44)
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PfK13 mutations leading to decreased PfK13 protein levels, impaired hemoglobin uptake and an elevated antioxidant capacity, are central to artemisinin resistance
The treatment also appeared to ameliorate cardiovascular risk, as endothelial function improved by the end of the treatment period
Unlike many peptides that degrade rapidly, BPC-157 has been noted for its stability and bioavailability
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