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RegeneRx Biopharmaceuticals conducted randomized, double-blind, placebo-controlled Phase 1A and 1B studies of intravenous TB4 administration in healthy volunteers, finding the drug safe and well tolerated
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These findings establish the mechanistic basis for the compound and provide proof of concept for its metabolic effects
Researchers have also investigated its contribution to experimental studies involving adipocyte biology, metabolic regulation, and intracellular energy pathways
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