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Impairment of vitamin B 12 absorption can cause megaloblastic anemia and neurologic disorders in deficient subjects
Its a catastrophic failure at the molecular level
One such option is Mounjaro (tirzepatide), a once-weekly injectable medication that was originally approved for type 2 diabetes and is now FDA-approved for weight management in adults with obesity or overweight and at least one weight-related health condition
they may potentially do so via the relatively permeable CVO or through endocytosis and transcytosis of vascular endothelial cells to reach the deep brain (143145)
After 14 days of treatment, the mice were euthanized via cardiac injection of sodium pentobarbitone given at 35 mg/kg
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