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nevertheless, a recent study has reported that this enzyme could be considered as an independent prognostic factor in colorectal cancer patients 52
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Glutathione not only functions as the substrate for protein S-glutathionylation but can also reverse the process by reducing the cysteine in proteins to which glutathione is disulfide bonded forming oxidized glutathione, GSSG
Therefore, further randomized studies are needed to understand HBOT in GBM before integrating it into standard clinical practice
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