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IV zinc differs in several ways: Delivered directly into circulation Avoids gastrointestinal irritation Allows for predictable absorption Can be combined with hydration and other supportive nutrients IV administration may be considered when oral intake is insufficient, poorly tolerated, or ineffective in meeting short-term physiological demand
+ Does it need to be stored frozen
Nrf2/ARE-dependent genes code for numerous mediators of the antioxidant response, including GCL, glutathione S-transferases (GSTs), thioredoxin, NAD(P)H quinone oxidoreductase 1 (NQO-1), and heme oxygenase 1 (HO-1) (21)
This "phospholipid bilayer" protects the glutathione as it passes through the harsh environment of the stomach
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