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Activation of invasion by oncogenic reprogramming of cholesterol metabolism via increased NPC1 expression and macropinocytosis
By inhibiting bacterial replication, it ensures the integrity of parenteral medications during repeated use from a single vial
doi:10.1016/S0006-291X(86)80358-8
Intrinsic (mitochondrial) pathways are also activated, with pro-apoptotic Bcl-2 family members (Bid, Bak, Bax) promoting mitochondrial outer membrane permeabilization, cytochrome C release, and apoptosome formation (cytochrome C + APAF-1 + procaspase-9)
: : (Gly) - (Glu) - (Pro) - (Pro) - (Gly) - (Lys) - (Pro) - (Ala) - (Asp) - (Asp) - (Ala) - (Gly) - (Leu) - (Val)
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