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Interestingly, the relationship goes both ways
Small, uncontrolled, open-label intervention studies have suggested a beneficial effect of acetyl-L-carnitine (ALCAR) in patients with painful neuropathies
However, it is unclear exactly which isoform acts in cardiomyocytes and how it exerts its anti-ferroptosis effect, which requires further study
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Microb Cell Fact 21:169 Colognato R, Laurenza I, Fontana I, Coppede F, Siciliano G, Coecke S, Aruoma OI, Benzi L, Migliore L (2006) Modulation of hydrogen peroxide-induced DNA damage, MAPLs activation and cell death in PC12 by ergothioneine
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