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A secondary consideration: ashwagandha's cortisol-modulating effects could theoretically influence blood glucose homeostasis in individuals already managing blood sugar with semaglutide

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Safety, Monitoring, and Who Should Consider Biomarker Assessment Patients reporting persistent body aches during GLP-1 treatment should inform their prescribing provider, who may recommend hydration optimization, electrolyte panel review, B-vitamin supplementation, or temporary dose stabilization

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[58] In severe intoxication, hemoperfusion or hemofiltration can be an effective means of hastening elimination of the drug from the body