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Oral semaglutide and cardiovascular outcomes: The overlooked variables [PMID: 40789549] Laboratory literature summary: Oral semaglutide and cardiovascular outcomes: The overlooked variables
Preparing these in advance means a difficult afternoon does not derail your week
In addition to bodyweight loss through lifestyle interventions, pharmacotherapies targeting adipose tissue, the digestive system (gut-liver axis) and/or inflammation are warranted
Patients with pre-existing cardiovascular conditions, uncontrolled hypertension, or structural cardiac abnormalities require particularly cautious evaluation, and stimulants may be contraindicated in certain high-risk individuals
As patents expire and potential generic or biosimilar versions emerge (e.g., generic liraglutide by Teva in 2024 ( [68] )), costs might come down, but for newer agents like semaglutide or tirzepatide, it could be years
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