Now we're understanding these effects: What are these results and how can we compliantly sell these products
FcRn antagonists likely block transplacental transport of IgG, as demonstrated for nipocalimab in an ex vivo placental transfusion model [341], and are unlikely to pass to the fetus, as the high affinity and limited pH-dependency of their binding to FcRn cause them to stay within FcRn-expressing cells, and not undergo extensive receptor-mediated transport
TRIM-EBC, a first-of-its-kind study directly testing whether medically assisted weight loss with tirzepatide can influence recurrence in people with a history of early breast cancer and overweight or obesity
Semaglutide has shown impressive results in clinical trials
These include not only effects of weight loss, but also improvements in endothelial function, reductions in low-grade inflammation (evidenced by a significant decrease in high-sensitivity C-reactive protein levels), and potential plaque stabilization [73]