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Abstract Background/Objectives: Glutathione (GSH) is the most abundant endogenous antioxidant and a critical regulator of oxidative stress
doi: 10.1016/j.msard.2019.101494 41 Medina-FernandezFJEscribanoBMAgueraEAguilar-LuqueMFeijooMLuqueEet al
A study using a three-dimensional tumour sphere model combined with CRISPR-Cas9 screening reported that Nrf2 overactivation was essential for lung tumour proliferation and survival, whereas silencing of Nrf2 predisposed spherical cells to ferroptosis, which was also consistent with clinical observations [77]
By the time he arrived, Benedi had slipped into a coma
Banasavadi-Siddegowda, Y
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