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"We don't really know why some people only lose 5% where some people are super responders and losing 30% of their body weight." Kushner thinks of the result as a kind of new settling point the medication helps establish, though why it lands so much lower for some people isn't well understood
Single-cell genomic approaches now enable systematic investigation of these mechanisms
Glucagon-like peptide 1 undergoes differential tissue-specific metabolism in the anesthetized pig
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