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A 2017 study (Kim et al., Diabetes Technology & Therapeutics ) found abdominal subcutaneous injections absorbed 15% faster than thigh injections and 23% faster than upper arm, likely due to higher regional blood flow
For the same 220-pound person, 22.5% means losing roughly 50 pounds, nearly 17 more pounds than semaglutide would produce on average
others develop more persistent bloating that affects daily comfort
For a side-by-side comparison of how semaglutide stacks up against the other major GLP-1 option, our semaglutide vs tirzepatide side effects guide compares the safety profiles in detail
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