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Applying a BER threshold of 3 to our dataset would be protective for all benchmark chemicals, only when including the transcriptomics PoDs for the high-risk exposure scenarios for Amiodarone and Crystalline silica

In addition, the follow-up duration of ELIXA was also relatively short (2.1 years), especially when compared with the follow-up duration of 5.4 years in the REWIND trial [60, 62]

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Clin Ther (2015) 37(1):22541.e8

It is a quaternary ammonium compound that the body synthesizes from the amino acids lysine and methionine, primarily in the liver, kidneys, and brain