Folate supplementation can normalize the hematologic abnormalities in vitamin B12 deficiency (thereby potentially obscuring or delaying diagnosis), but even patients who are not taking folate supplements may have no evident hematologic abnormalities despite symptomatic vitamin B12 deficiency
Homocysteine and vascular disease The pathologist, Kilmer McCully, proposed the homocysteine theory of atherosclerosis in the 1960s after comparing the vascular pathologies of two young children who died of thromboembolic disease
The application in Homeopathy happened from the arsenic toxicological observations on the human being, being used in these circumstances, of course, dilested, when these effects are not observed
Dosage adjustments may be necessary based on patient response and ongoing monitoring
For example, the antibiotic chloramphenicol can interfere with the effects of vitamin B, reducing the expected hematologic response to B therapy