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The most common issues include mild digestive upset in 3-5% of users, typically resolving within the first week of use

While the exact cause is not fully understood, genetic predisposition, stress, and other immune-related factors are believed to contribute to its onset

MSU crystals display a triclinic structure composed of stacked sheets of purine rings, forming needle-shaped crystals observable under microscopy

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Previous work has shown that patients often do not disclose the complementary medicines they use to their physicians but practice these remedies on their own [7577]