But with GLP-1s, everyone is kind of iterating in real time. Some recent iterations: Last month, Eli Lilly announced that its phase 3 trial for retatrutide a triple agonist dubbed Godzilla that activates GLP-1, GIP, and glucagon receptors appears to exceed the performance of other weight-loss medications
And if something doesnt feel right, talking to a doctor can bring clarity and peace of mind
In the STEP trials, semaglutide 2.4 mg weekly showed average weight reductions of 1215% of body weight over 68 weeks, whilst in the SCALE trials, liraglutide 3 mg daily typically produced 58% weight loss
It's important to note that while some medications in this class have demonstrated cardiovascular benefits in clinical trials, Saxenda is not indicated for cardiovascular risk reduction
Dietary composition matters beyond total calories