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Barber MF, Michishita-Kioi E, Xi Y, Tasselli L, Kioi M, Moqtaderi Z, et al
The cycle structure exists for a practical reason: continuous stimulation of the same receptor pathways can lead to reduced sensitivity over time, and a rest period allows the system to reset before the next cycle produces full effect
Finally, GSH availability negatively regulates SLC25A39 protein abundance, coupling redox homeostasis to mitochondrial GSH import in mammalian cells
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