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Even though there usually is remarkable variability in individual capacity for weight loss in response to pharmacological agents [36], these results might suggest that patients with poor metabolic long-term outcomes following BS are less likely to benefit from add-on pharmacotherapy
Earlier oral GLP-1 drugs, such as semaglutide (Rybelsus), are peptide-based, which means they are easily broken down by stomach acid and digestive enzymes
Studies directly comparing tirzepatide and semaglutide have shown that tirzepatide generally leads to more significant weight loss
for tirzepatide, its 2.5 mg
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