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Metformin inhibited proliferation and metastasis of colorectal cancer and presented a synergistic effect on 5-FU

Compared to other antidiabetic medications, including metformin, sulfonylurea, thiazolidinediones (TZDs), dipeptidyl peptidase-4 (DPP-4) inhibitors, sodium-glucose cotransporter-2 (SGLT-2) inhibitors, and insulins, GLP-1-RAs boast a combination of high efficacy in glycemic control, desirable function of weight loss, low risk of hypoglycemia, and even a mild benefit on the cardiovascular system

Invest Ophthalmol Vis Sci 2003

In injury contexts, angiogenesis is crucial

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