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This effect was associated with upregulation of hydroxyindole-O-methyltransferase (HIOMT), a key enzyme in melatonin biosynthesis (Khavinson & Anisimov, Neuroendocrinology Letters, 2000)
The Abdulghani study directly compared a topical copper peptide to tretinoin and found superior tolerability with comparable or greater collagen improvements
Why it matters for body composition: Smaller fat cells mean less inflammation and better insulin sensitivity, two key components for losing fat while preserving muscle
No FDA-approved human trial
Better Sleep : B12 helps regulate your sleep-wake cycle, contributing to more restful and rejuvenating sleep
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