Average weight loss was about 22 kg, and the authors report 92% of it came from fat, with muscle largely spared, particularly interesting since muscle loss is the big concern with GLP-1 drugs
Journal of clinical medicine, 12(1), 145
In this study, we did not observe significant increases in extracellular cAMP release in coronary effluent from GLP-1(2836)perfused mouse hearts (Figure 2B) as compared with robust responses in caSMCs and caECs in vitro (Figure 3, A and B)
In another trial using 15 mg of tirzepatide (the maximum dose of Mounjaro and Zepbound), patients lost just over 20% of their body weight after 72 weeks
A dermonutrient containing special collagen peptides improves skin structure and function: a randomized, placebo-controlled, triple-blind trial using confocal laser scanning microscopy on the cosmetic effects and tolerance of a drinkable collagen supplement