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Subclinical intestinal inflammation in patients with Crohn's disease following bowel resection: a smoldering fire
The FDA-approved prescribing information for these medications lists gastrointestinal adverse effectsincluding nausea, vomiting, diarrhea, and in some cases eructation (belching)as common side effects
Common side effects (usually temporary): Nausea (most frequent, especially after injections) Constipation or loose stools Fatigue and low energy in the first few weeks Reduced appetite (this is also the intended effect) Injection site reactions Less common but serious: Pancreatitis (seek care immediately if you have severe abdominal pain) Gallbladder problems Changes in heart rate Rare thyroid concerns (see contraindications above) Staying well hydrated is important throughout treatment
The range is wide because trials used different patients and different routines
These include pathways involved in cell migration, collagen formation, and extracellular matrix organization
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