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Staying within regulated pathways is the safest way to explore new therapeutic options
MADs are effective in the treatment of OSA, with improvements seen in AHI, oxygen desaturation index, sleepiness, and sleep-related quality-of-life, in addition to improvements in blood pressure by 24 mmHg among patients with hypertension, comparable to PAP [36]
Patients should consult their healthcare providers and be informed about avoiding these risks
Research limitations The most significant safety consideration involves research limitations
While its role in increasing energy expenditure is the most talked-about feature, its cardiovascular implications are just as important to understand
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