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Vegetarian:Yes

Acknowledgements The authors would like to thank Servier, Marcel Tisch, B-Gideon-Bergheim, Long Li, Fang-fang-yang, Helicase 11 & Rahel-Khdhr for allowing us to use and modify their illustrations available at Bioicons.com and SciDraw.io in our figures

Avoid stimulating activities during the wind-down period, including work emails, social media, news, intense exercise, and emotionally charged conversations

Although the contribution of an excessive intake of methionine has not been clinically proven, folate deficiency (associated or not with the thermolabile mutation of MTHFR) and vitamin B 6 deficiency (perhaps associated with heterozygosity for CBS deficiency or with methionine excess) would be strongly involved in the incidence of cardiovascular disease associated with moderate hyperhomocysteinemia

Polyspecific organic cation transporters: structure, function, physiological roles, and biopharmaceutical implications