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(2000) focused on male Wistar rat pups weaned at 20 days of age and assigned to either a control diet or a ketogenic diet containing MCT oil
In baseline animal testing, major dsip side effects or severe toxicities are rarely documented when adhering to exact parameters
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Garcia-Echeverria et al (2004) presented a new compound (a pyrrolo[2,3-d] pyrimidine) that although inhibiting the IGF-1R and IR TK equipotently in cell-free systems, exhibited several-fold selectivity for the IGF-1R in a cellular context and reduced the growth of IGF-1R positive fibrosarcomas in vivo
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