Rapid weight loss or prolonged low intake can make it easier to lose muscle along with body fat
At each visit: Weight and body composition measurements Blood pressure and heart rate Appetite and appetite suppression assessment GI tolerance and other side effects Medication adherence and injection technique Protein intake and exercise consistency Laboratory monitoring occurs at Month 3 (comprehensive panel), Month 6, and Month 12, then annually
A 2025 head-to-head clinical trial comparing FDA-approved tirzepatide to FDA-approved semaglutide for obesity found that tirzepatide produced greater reductions in body weight over 72 weeks
The gastrointestinal side effects commonly associated with semaglutideparticularly nausea, vomiting, and diarrheacan lead to reduced fluid intake and increased fluid losses
(Ozempic is approved for managing blood sugar levels in people with type 2 diabetes.) People with obesity (body mass index of 30 or more) also may need higher vitamin D intake because the vitamin gets If you have diabetes or obesity or think you might not be getting enough vitamin D while taking Ozempic, talk with your healthcare professional