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This process is thought to occur in two phases, first the mobilization of cytochrome c and then its translocation through permeabilized OMM
Encapsulation and enzyme-mediated release of molecular cargo in polysulfide nanoparticles
In addition, aberrant Ca 2+ signaling causing mitochondrial dysfunction can adversely affect neurotransmitter signaling and lead to excitation/inhibition imbalance [94, 97, 98]
12,13 Related studies have added that DAC can up-regulate the expression of PD-L1 in metastatic colorectal cancer, which may make PD-1/PD-L1 inhibitors more likely to play a role, that is, the combination of DAC and anti-PD-1/anti-PD-L1 antibodies may be a potential treatment for radiosensitization of osteosarcoma
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