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However, the situation changes dramatically when weight loss is part of a treatment plan for a diagnosed medical condition
Some people maintain better results through intensive behavioral interventions, but continuing medication at reduced doses provides the most reliable maintenance strategy
Alcohol increases the risk of pancreatitis by direct pancreatic inflammation and by promoting heavy drinking patterns in some people
Existing observational studies comparing weight reduction with these two treatments were conducted in patients with and without type 2 diabetes before FDA approval of tirzepatide for obesity management [8,9,10,11,12,13,14,15]
Phase 3 trials are the large-scale, randomised controlled studies required to establish efficacy and safety across diverse patient populations before a regulatory submission can be made
