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For a typical subject with type 2 diabetes and a body weight of 85 kg, clearance was estimated to be 0.0348 L/h (95% CI 0.03270.0369 L/h) and the total volume of distribution was estimated to be 7.7 L ( V c + V p
However, Wegovy 7.2mg, now approved in the UK since January 2026, has produced results comparable to Mounjaros highest dose, with 33.2% of participants achieving 25%+ weight loss
Dont prematurely resume normal eating
Semaglutide May Be a Better Fit For: Individuals sensitive to gastrointestinal side effects Those needing moderate appetite regulation rather than maximal suppression People prioritizing long-term tolerance and sustainability Tirzepatide May Be a Better Fit For: Individuals with significant insulin resistance Those who did not respond adequately to GLP-1 therapy alone People who tolerate incretin-based medications well Response is highly individual
S., Moszczynska, A., Mattina, K., Ang, L.-C., Boileau, I., Furukawa, Y., Sailasuta, N., & Kish, S
