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The trial record is summarized in Stier, Vos, and Kenleys 2013 paper
4 www.fda.gov/news-events/press-announcements/fda-approves-new-drug-treatment-chronic-weight-management-first-2014
Provides powerful antioxidant protection against free radical damage
PubMed 55.Bjorner JB, Lyng Wolden M, Gundgaard J, Miller KA
This ensures that NRF2 remains at low levels under normal conditions but can be rapidly activated under stress conditions, helping the cell cope with oxidative damage and other harmful stimuli
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