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In our previous study, we reported that the regenerative signaling, IL-6/STAT3 pathway, was strongly activated from 12 to 24 h after GalN injection followed with the significant upregulation of the marker of proliferation, histone H3 mRNA at 24 h in proline group

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GST catalyzes the conjugation of reduced glutathione to electrophilic xenobiotics and utilizes reduced glutathione to scavenge potentially toxic compounds

This integrated model is useful, but it remains provisional

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