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J Urol 2006;175:2115-8
Going back to the IEL cells for a moment, in Crohns disease and ulcerative colitis (UC) these cells can start to attack the gut lining itself, this further creates a cytotoxic environment, which can further exacerbate IELs to produce pro-inflammatory proteins, this can lead to a compromised intestinal lining, along with alterations in the gut microbiome
Indian Journal of Endocrinology and Metabolism, 28(6), 555-566
Essential for proper peptide handling
GLP1 RAs act precisely on those pathways
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