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Generalmente, la dosis estndar oscila entre 500 y 2000 mg por da
Role of metformin in the management of polycystic ovary syndrome
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Specific hereditary backgrounds are implicated, such as FOXP3 pathogenic variants in immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome, and autoimmune regulator (AIRE) mutations in APS type 1 (Klubo-Gwiezdzinska And Wartofsky 2022)
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