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Saxenda for obesity) was once the most prescribed GLP-1, before being eclipsed by semaglutide (Ozempic/Wegovy) and tirzepatide (Mounjaro/Zepbound)
Some patients respond well before reaching higher doses
Evidence suggests that weight loss is associated with blood pressure reduction
Both agents target different pathways in glucose control and appetite regulation, raising the question of whether combining them amplifies results or creates safety concerns
Changes may include looser clothing, a smaller waistline, steady week-to-week progress, and increased motivation
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