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This streamlined solution enhances efficiency and ease of use in research applications
Conditions include alcoholic liver disease, viral hepatitis, cirrhosis, and primary or metastatic liver cancer Renal dysfunction : Impaired kidney function reduces B12 elimination, causing accumulation even with normal intake Haematological conditions : Myeloproliferative neoplasms, chronic myeloid leukaemia, polycythaemia vera, and hypereosinophilic syndrome increase transcobalamin production, elevating total serum B12 Laboratory interference : Macro-B12 (immunoglobulin-bound B12) and assay interference can cause spuriously elevated results without true excess In clinical practice, unexplained hypercobalaminaemia should prompt investigation for underlying disease, particularly in patients without obvious supplementation history
It is designed for oral consumption in capsule form
Zhong, Nanosuspension drug delivery system: preparation, characterization, postproduction processing, dosage form, and application, in Nanostructures for Drug Delivery, Elsevier, 2017, pp
Fatigue can occur rarely
