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Examination and initial investigations Recommended minimum evaluation for new or worsening vaginal symptoms in a semaglutide-treated patient generally mirrors standard care: External vulvar inspection for dermatoses (lichen sclerosus, eczema/contact dermatitis), fissures, atrophy signs

She remains on hormonal therapy, no longer needs compression and is back to regular exercise without impairment

doi: 10.1530/edm-23-0017

Indeed, recent guidelines published by the EASD have indicated GLP-1 receptor agonists and SGLT-2 inhibitors as treatments for patients with high cardiovascular risk [12]

Louis, MO), editor-in-chief of Circulation: Heart Failure , said that clearly, this idea that adipose tissue is bad and less adipose tissue is good is becoming a very strong theme. Its not surprising that patients with the most-severe obesity derived the greatest benefits in terms of quality of life in SUMMIT, she added, but said its reassuring that there isnt some level of obesity thats so great that you dont benefit. Obesity Severity in SUMMIT In the United States, about two-thirds of patients with HFpEF have the obesity phenotype, and the pathophysiological abnormalities present in this setting all correlate to the amount of excess body weight, and body fat in particular, Borlaug said