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Dose Response
Although after 4 to 6 injections if they do not feel any benefits then there is a possibility that the B12 is more than likely not going to be effective
Angiogenesis is essential for tissue healing because new blood vessels deliver oxygen, nutrients, and repair cells (fibroblasts, stem cells, immune cells) to damaged areas
Arterioscler Thromb Vasc Biol 19 : 13161324
Where does the available human evidence sit on the study design hierarchy: case report (low grade), retrospective series, or controlled trial (higher grade)
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