So people at greatest risk for deficiency include those with low stomach acid (e.g., older adults and people on proton pump inhibitors or antacids) or low IF production (known as pernicious anemia), people on medications that interfere with B12 absorption (such as metformin), people who have had gastric surgery, those with GI conditions that impair nutrient absorption (like celiac or Crohn's disease), and people on vegan and vegetarian diets
How long does liposomal glutathione take to work
Those with certain genetic variations affecting b12 metabolism may benefit from methylcobalamin specifically
Clinical trial data shows that discontinuation of GLP-1 therapy typically results in return of appetite, food preoccupation, and weight regain, indicating that ongoing treatment may be necessary to maintain the reduction in food noise for many individuals
Baak LM, Wagenaar N, van der Aa NE, et al