FIGURE 1 Given the role of GLP-1 in glycaemic control, the anti-apoptotic, growth-stimulating and insulin secretion-promoting effects on pancreatic -cells, the ability to re-sensitize the cellular insulin-signaling, minor side effects, good tolerance by normoglycemic patients and the fact that GLP-1 does not desensitize, synthetic GLP-1R agonists have been on the market for decades to treat type 2 diabetes mellitus (T2DM) or, more recently, to improve weight loss (Drucker, 2018)
These symptoms often appear during the first few weeks of treatment or after a dose increase
Human studies, while smaller in scale, support both efficacy and safety over extended periods
Dose splitting Some providers recommend splitting the weekly dose into two smaller injections given 3 to 4 days apart
Lipostat+ injections are ideal for individuals looking to support their weight loss journey and improve fat metabolism