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eds.) 15791593 (Springer International Publishing, 2022)
Lactate is now recognized not only as a metabolic intermediate but also as a signaling mediator and regulatory molecule that orchestrates diverse physiological and pathological processes through metabolic, immune, and epigenetic mechanisms
Kornienko IV, Aramova OY, Tishchenko AA, Rudoy DV, Chikindas ML
North KN, et al
For example, Angong Niuhuang Wan inhibits the accumulation of ROS and Fe 2+ and improves mitochondrial dysfunction and BBB structural integrity by activating the PPAR/AKT/GPX4 pathway, thereby enhancing neurological function in rats with ischemic stroke and reducing cerebral infarction volume
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