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The semaglutide and tirzepatide trials changed that expectation: Semaglutide 2.4 mg once weekly produced average weight loss around 15% at ~68 weeks in adults without diabetes, with a substantial fraction of participants losing 1520% of baseline weight
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In astrocytes, this function may be crucial for maintaining their own robust antioxidant reservoir, enabling them to effectively buffer neuronal oxidative stress and neutralize lipid peroxides
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& Liu, S
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