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Empagliflozin reverses late Na + current enhancement and cardiomyocyte proarrhythmia in a translational murine model of heart failure with preserved ejection fraction
Furthermore, they are labile, undergo hydrolysis and pH-dependent intramolecular acyl migration to isomeric conjugates of glucuronic acid, and may react irreversibly with plasma proteins, tissue proteins, and with nucleic acids
doi: 10.1002/(SICI)1096-8628(19990730)85:3 3.0.CO;2-X 205 SilvaJ.MakW.ZvetkovaI.AppanahR.NesterovaT
-Glutamylcyclotransferase (GGCT), a key metabolic enzyme frequently overexpressed in various cancers, has an undefined role in directing glutamine metabolic flux during tumorigenesis
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